Natural progesterone supplement sources

Here are the low-excipient natural progesterone supplements that I am aware of. Please leave a comment if you know of other sources, have feedback about any of the suppliers, or just have suggestions on improving the page.

From what I've observed, Progest-E seems like the most popular product, and Ona's Natural comes out the most affordable. I haven't heard of a lot of people using Ona's though, so I'd be particularly curious to from people that have used it.

Bottle of Ona's Natural ProgesteroneOna's Natural 10% Progesterone Oil


USP progesterone (yam-derived), vitamin E (sunflower/soy-derived, non-GMO, mixed tocopherols), fractionated coconut oil.


Cost: $6.39 per gram of progesterone.

I've only seen Ona's Natural available direct. It ships internationally from California.

They also have higher-concentration (up to 20%) progesterone creams.

Bottle of Progest-EProgest-E


Yam-derived USP progesterone, vitamin E as d-alpha tocopherol and/or mixed tocopherols, vegetable triglycerides (from olive or coconut).

There may have been an issue with the manufacturer or one of the suppliers recently, so be sure to monitor the taste of the oil.


Cost: typically around $11.40 per gram of progesterone.

Shipping from the US

Shipping from the UK

Bottle of ProgestelleProgestelle


Yam-derived USP progesterone, coconut oil.

There is a theory that Dr. Peter Eckhart of Women's Therapeutic Institute (makers of Progestelle) is actually some kind of marketing pseudonym. I have no idea if that's true, but I choose to imagine that this is his work uniform:

Shoddy doctor shirt costume

Update: see the comment below for more information on Dr. Eckhart's credentials / identity.


Cost: $30.00 per gram of progesterone.

Bottle of ProgestineProgestene


USP progesterone, SFA esters, ethanol (Ray Peat has mentioned disliking combinations of progesterone and alcohol here, but the comments are also worth a look for the company's founder defending the product formulation).

Progestene is intended for lab/research use only.


Cost: $41.65 per gram of progesterone.

Progestene is only available directly from IdeaLabs. It ships internationally from the US.

Logo for Simply ProgesteroneSimply Progesterone


Progesterone, mixed tocopherols, MCT oil.


Cost: around $8.51 per gram of progesterone.

Testing progesterone levels

I haven't heard one way or another whether it's useful to track your progesterone with bloodwork, but I've compiled a list of progesterone blood test providers if you're curious to know your levels. It runs in the $50-$200 range depending on which company you order the test from.

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