Glycine supplements with the fewest additives

Glycine may be an underrated amino acid, but some glycine supplements can have undesirable excipients.

I try to avoid those extra ingredients because they may have questionable health effects. If you want to do the same, my recommendations for glycine supplements are:

Recommended as purest glycine capsules:

These brands contain have vegetable capsules made with hydroxypropyl methylcellulose, which probably isn't a big deal, but makes me prefer the powders in the next section if you don't need the convenience of a capsule.

Photo of Metabolic Maintenance Glycine (Veggie Capsules)
Metabolic Maintenance Glycine (Veggie Capsules)
Available on metabolicmaintenance.com
Positives:
  • silica-free / silicon-dioxide-free
Negatives:
  • contains hypromellose / hydroxypropyl methylcellulose
All ingredients:

Glycine, vegetarian cellulose capsule (Metabolic maintenance told me this is pine tree bark-based, which almost certainly means hydroxypropyl methylcellulose).

Metabolic Maintenance has promised me a Certificate of Analysis, I will post it when I receive it.

Photo of Nutrabio Glycine (Veggie Capsules)
Nutrabio Glycine (Veggie Capsules)
Available on nutrabio.com
Positives:
  • silica-free / silicon-dioxide-free
Negatives:
  • contains hypromellose / hydroxypropyl methylcellulose
All ingredients:

Glycine, vegetable capsule (NutraBio told me this is hydroxypropyl methylcellulose and water).

Recommended as purest glycine powders:

Glycine doesn't taste unpleasant, so a powder form can be convienently added to drinks.

Photo of BulkSupplements Glycine Powder
BulkSupplements Glycine Powder
Available on Bulk Supplements
Positives:
  • silica-free / silicon-dioxide-free
  • hypromellose-free / hydroxypropyl methylcellulose-free
Negatives:
(none)
All ingredients:

Glycine powder.

Certificate of Analysis available (for lot #12101222). The country of origin is Cambodia. I'm not sure whether it's from an independent lab or not.

Photo of Metabolic Maintenance Glycine Powder
Metabolic Maintenance Glycine Powder
Available on metabolicmaintenance.com
Positives:
  • silica-free / silicon-dioxide-free
  • hypromellose-free / hydroxypropyl methylcellulose-free
Negatives:
(none)
All ingredients:

Glycine powder.

Metabolic Maintenance has promised me a Certificate of Analysis, I will post it when I receive it.

Photo of Metabolic Maintenance Glycine Sticks
Metabolic Maintenance Glycine Sticks
Available on metabolicmaintenance.com

These sticks let you conveniently get 3 grams of pure glycine at a time.

Positives:
  • silica-free / silicon-dioxide-free
  • hypromellose-free / hydroxypropyl methylcellulose-free
Negatives:
(none)
All ingredients:

Glycine powder.

Metabolic Maintenance has promised me a Certificate of Analysis, I will post it when I receive it.

Photo of Now Foods Glycine Powder
Now Foods Glycine Powder
Available on iHerb
Positives:
  • silica-free / silicon-dioxide-free
  • hypromellose-free / hydroxypropyl methylcellulose-free
Negatives:
(none)
All ingredients:

Glycine powder.

Now Foods was unable to send me a Certificate of Analysis, but told me that the product is tested for purity. The country of origin "includes Japan/Korea/China".

Positives:
  • silica-free / silicon-dioxide-free
  • hypromellose-free / hydroxypropyl methylcellulose-free
Negatives:
(none)
All ingredients:

Glycine powder.

PowderCity L-Glycine
Available on Powder City
Positives:
  • silica-free / silicon-dioxide-free
  • hypromellose-free / hydroxypropyl methylcellulose-free
Negatives:
(none)
All ingredients:

Glycine powder.

Certificate of Analysis available (for lot #141202, reported July 6, 2015). The country of origin is China, as of September 2015. I believe PowderCity always has their latest COA in the product images.

Photo of PureBulk Glycine Powder
PureBulk Glycine Powder
Available on PureBulk
Positives:
  • silica-free / silicon-dioxide-free
  • hypromellose-free / hydroxypropyl methylcellulose-free
Negatives:
(none)
All ingredients:

Glycine powder.


Other glycine supplements

The following are other glycine supplements I'm aware of, sorted alphabetically.

Name Ingredients
Carlson Glycine (Powder)

Glycine powder.

COA unavailable ("company policy states that we are not to share these CofAs with the public"). Country of origin unavailable ("We do not specify a country of origin for our raw materials").

Country Life Gluten Free Glycine (Tablets)

Cellulose, stearic acid, cellulose & glycerin coating, silica, magnesium stearate, vegetable glaze.

Solgar Glycine (Veggie Capsules)

Vegetable cellulose, microcrystalline cellulose, vegetable magnesium stearate, vegetable stearic acid. The capsule is probably hypromellose / hydroxypropyl methylcellulose.

Source Naturals Glycine (Gelatin Capsules)

Gelatin (capsule), microcrystalline cellulose, colloidal silicon dioxide, and magnesium stearate, hypoallergenic: contains no yeast, dairy, egg, gluten, corn, soy or wheat.

The glycine is from China (based on correspondence in September 2015). It was previously from Japan.

Thorne Research Glycine (Veggie Capsules)

Hypromellose (derived from cellulose) capsule. May contain silicon dioxide.

Life Extension Glycine (Veggie Capsules)

Glycine, vegetable cellulose (capsule), ascorbyl palmitate. The capsule is probably hypromellose / hydroxypropyl methylcellulose. The glycine itself is made in the US.

Pure Encapsulations Glycine (Veggie Capsules)

Glycine (free-form), vegetable cellulose (capsule), ascorbyl palmitate, hypo-allergenic plant fiber (cellulose from pesticide-free Southern pine, probably hydroxypropyl methylcellulose), vegetarian capsule (cellulose from pesticide-free Southern pine, probably hydroxypropyl methylcellulose, water).

Now Foods Glycine

Glycine (free-form), gelatin (capsule), magnesium stearate (vegetable source), silica.


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